function
resolution of chromosome dimers
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.3|DNA condensation/ segregation][SW|Categories] containing this gene/protein
[SW|DNA condensation/ segregation]Gene
Coordinates on the chromosome (coding sequence)
3,049,725 -> 3,052,583
The protein
Catalyzed reaction/ biological activity
aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity [Pubmed|19818024]the two DNA translocases [protein|search|SftA] and [SW|SpoIIIE] synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively [Pubmed|21239579]Paralogous protein(s)
[SW|SpoIIIE]Structure
[PDB|2IUT] (FtsK from ''Pseudomonas aeruginosa'', partial, 48% identity, complex with [SW|SpoIIIE]) [Pubmed|16916635][SW|Localization]
Cytoplasm (Homogeneous) [Pubmed|16479537]co-localizes with [protein|search|FtsZ] at nascent division sites [Pubmed|19788545][SW|Interactions]
forms a hexamer [Pubmed|19818024]Biological materials
Mutant
1A984 ( ''sftA''::''spec''), [Pubmed|19788545], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A984&Search=1A984 BGSC]BKE29805 (''[protein|search|sftA]''::''erm'', available in the BGSC, in [SW|Fabian Commichau]'s, and in [SW|Jörg Stülke]'s lab)References
Reviews
Original publications
16479537,19788545,19818024,21239579,16916635,27891124 
