pssA [2017-8-11 16:0:3]

phosphatidylserine synthase

locus: BSU02270

pI: 7.88

mw: 19.47 kDa

protein length: 177 aa

gene length: 531 bp

function: biosynthesis of phospholipids

product: phosphatidylserine synthase

essential: no

ec: 2.7.8.8

synonyms: pss

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.2|Biosynthesis of phospholipids]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 247,744 → 248,277

The protein

Catalyzed reaction/ biological activity

• CDP-diacylglycerol + L-serine = CMP + (3-sn-phosphatidyl)-L-serine (according to Swiss-Prot)

Protein family

• CDP-alcohol phosphatidyltransferase class-I family (according to Swiss-Prot)

[SW|Localization]

• cell membrane at the septum [Pubmed|15743965]

Expression and Regulation

Operons

• genes: [gene|27FB777AEBCC794A5A768C7FE7D8374BCEA75913|ybfK]-[gene|DE49797486CEC172F912D26A6BF2223190BF5DAD|pssA]-[gene|B2C089DCE51CA0CB11947FCD6F4EFAFF66269829|ybfM]-[gene|F34915697F3EF05E6A683055F46346C73F25CAFC|psd]
  description: [Pubmed|22383849,14762009]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|14762009], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|E77364F274A520FCCA9F5C9504E317B047BA29E6|SigX]: sigma factor, [Pubmed|14762009], in [regulon|E77364F274A520FCCA9F5C9504E317B047BA29E6|SigX regulon]

References

Reviews

• 9370336

Original publications

• 14762009,18820022,9422599,8829529,15743965,28376879