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thiL [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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thiL [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

thiamine-monophosphate kinase
locus
BSU05900
pI
5.04
mw
35.00 kDa
function
biosynthesis of thiamine
product
thiamine-monophosphate kinase
essential
no
ec
2.7.4.16
synonyms
ydiA, ydxA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.3|Biosynthesis/ acquisition of thiamine]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors]

    • Gene

    Coordinates on the chromosome (coding sequence)
    640,662 -> 641,639

    The protein

    Catalyzed reaction/ biological activity

  • ATP + thiamine phosphate = ADP + thiamine diphosphate (according to Swiss-Prot)

    • Protein family

  • thiamine-monophosphate kinase family (according to Swiss-Prot)

    • Structure

  • [PDB|1VQV] (from ''Aquifex aeolicus'', 33% similarity, 51% identity)

    • Expression and Regulation

    Operon

  • ''[protein|search|thiL]-[protein|search|tsaE]-[protein|search|tsaB]-[protein|search|ydiD]-[protein|search|tsaD]'' [Pubmed|22383849]

    • References

    Reviews

  • 19348578

    • Original publications

  • 16291685,22383849