adk [Mon Aug 31 2015 13:52:00 GMT+0200 (CEST)]

adenylate kinase

locus: BSU01370

pI: 4.45

mw: 23.00 kDa

function: ADP formation

product: adenylate kinase

essential: yes

ec: 2.7.4.3

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.1|Biosynthesis/ acquisition of purine nucleotides]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of nucleotides], [SW|essential genes]

This gene is a member of the following [SW|regulons]

• [SW|stringent response]

Gene

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• ATP + AMP = 2 ADP (according to Swiss-Prot)

Protein family

• adenylate kinase family (according to Swiss-Prot)

Structure

• [PDB|1P3J]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Regulation

• [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]

References

• 8635744,18093993,21145325