SubtiBank SubtiBank
cotS
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cotS

outer spore coat protein
locus
BSU_30900
pI
6.64
mw
40.93 kDa
protein length
351 aa Sequence Blast
gene length
1056 bp Sequence Blast
function
resistance of the spore
product
spore coat protein
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V]

    • Gene

    Coordinates
    3,159,691 → 3,160,746

    The protein

    Protein family

  • cotS family (with [protein|D57116C65FD11EF92FB5D2945B10A1D024AEFF22|CotI] and [protein|0F40291BB10DB6D7DFD94B9C7D700F4410C4EE69|YutH], according to UniProt)

    • Structure

  • [PDB|2Q83] ([protein|D57116C65FD11EF92FB5D2945B10A1D024AEFF22|CotI], 26% identity) [pubmed|20077512]

    • [SW|Localization]

  • outer spore coat, localization depends on [protein|825AD8D4315A85CD384F9AF6AD894E38E57C88F7|CotE] [Pubmed|22171814]

    • Expression and Regulation

    Operons

    genes
    [gene|2C17028E7DC755FFC190397AC6509E383C4DF99A|cotSA]-[gene|DC99E507696A1CB23140A1CBA45DA07D1F7C7D53|cotS]-[gene|5A13CEBB6820454E38DE81C1663078531B2AE4C2|ytxO]
    description
    [Pubmed|9603889]

    sigma factors

  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15699190,9603889], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]

    • regulatory mechanism

  • [protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE]: activation, [Pubmed|15383836], in [regulon|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE regulon]

    • regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190,9603889]
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    Biological materials

    Mutant

  • BKE30900 (Δ[gene|DC99E507696A1CB23140A1CBA45DA07D1F7C7D53|cotS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE30900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGGTACACTCTGTTCACCC, downstream forward: _UP4_AAAGCGTATCGGGAGGCGAA
  • BKK30900 (Δ[gene|DC99E507696A1CB23140A1CBA45DA07D1F7C7D53|cotS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK30900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGGTACACTCTGTTCACCC, downstream forward: _UP4_AAAGCGTATCGGGAGGCGAA

    • References

    Reviews

  • 23202530

    • Original publications

  • 11737650,7545510,9603889,14702409,10234840,15699190,22171814,15383836,26953338,20077512