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bdbA [Sun Dec 04 2016 12:35:46 GMT+0100 (CET)]
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bdbA [Sun Dec 04 2016 12:35:46 GMT+0100 (CET)]

thiol-disulfide oxidoreductase
locus
BSU21460
pI
8.00
mw
16.00 kDa
function
oxidative folding of proteins
product
thiol-disulfide oxidoreductase
essential
no
synonyms
yolI

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.2|Chaperones/ protein folding]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|chaperones/ protein folding], [SW|SP-beta prophage]
  • This gene is a member of the following [SW|regulons]

  • [SW|Abh regulon], [SW|AbrB regulon], [SW|Rok regulon], [SW|YvrHb regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,266,936 -> 2,267,349

    The protein

    Protein family

  • thioredoxin family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[SW|sunA]-[SW|sunT]-[SW|bdbA]-[SW|sunS]-[SW|bdbB]'' [Pubmed|22383849]
  • Regulation

  • repressed by [protein|search|Rok]-[SW|DnaA] [Pubmed|27902860,15743949]
  • Regulatory mechanism

  • activated by [SW|YvrHb] [Pubmed|16306698]
  • repressed by [protein|search|Rok]-[SW|DnaA] [Pubmed|27902860,15743949]
  • [protein|search|AbrB]: transcription repression[Pubmed|20817675]
  • [protein|search|Abh]: transcription activation [Pubmed|20817675]
  • Additional information

  • the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]
  • References

  • 27902860,11872755,15743949,21815947,20817675