rpmEB [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

general stress protein, binds in the stationary phase to the ribosome, replaces RpmE under conditions of zinc limitation

locus: BSU30700

pI: 9.00

mw: 9.00 kDa

function: survival of salt stress

product: accessory ribosomal protein

essential: no

synonyms: rpmE2, ytiA

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|general stress proteins (controlled by SigB)], [SW|phosphoproteins]

This gene is a member of the following [SW|regulons]

• [SW|SigB regulon], [SW|Zur regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,138,978 -> 3,139,226

The protein

Protein family

• Type B subfamily (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|RpmE]

Modification

• phosphorylated on Arg-70 [Pubmed|22517742]

Expression and Regulation

Operon

• ''[protein|search|ytiA]'' [Pubmed|22383849]

[SW|Sigma factor]

• [protein|search|SigB] [Pubmed|15805528]

Regulation

• induced by stress ([protein|search|SigB]) [Pubmed|15805528]
• induced by zinc starvation ([protein|search|Zur]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12904577,15049826 PubMed]
• part of the first wave of induction upon zinc depletion [Pubmed|27561249]

Regulatory mechanism

• [protein|search|Zur]: transcription repression in the presence of zinc [http://www.ncbi.nlm.nih.gov/sites/entrez/12904577,15049826 PubMed]

References

• 17163968,15049826,16547061,12904577,22383849,15805528,19648245,22517742,23002217,27561249