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csaA [Fri Nov 06 2015 10:27:01 GMT+0100 (CET)]
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csaA [Fri Nov 06 2015 10:27:01 GMT+0100 (CET)]

molecular chaperone involved in protein secretion
Locus
BSU19040
Isoelectric point
8.00
Molecular weight
11.00 kDa
Function
protein secretion
Product
molecular chaperone
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Protein secretion

    • Categories containing this gene/protein

  • protein secretion, membrane proteins

    • Gene

    Coordinates on the chromosome (coding sequence)
    2,079,214 -> 2,079,546

    Phenotypes of a mutant

  • From unsuccessful trials to knock out the gene it was concluded that csaA apparently is essential. However, in a conditional mutant (Pspac-csaA), depletion of the gene product is not lethal. But secretion of some proteins including SdpC was reported to be affected unter such conditions.PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • Secretion associated chaperone. Assumed functional analogue of E. coli SecB

    • Protein family

  • FIG1 subfamily (according to Swiss-Prot)

    • Domains

  • CsaA contains a tRNA binding domain.

    • Structure

  • 2NZO

    • Localization

  • cell membrane (according to Swiss-Prot)

    • Interactions

  • CsaA-SdpC PubMed
  • CsaA-SecA PubMed
  • CsaA-CsaA

    • Additional information

  • The functional entity of CsaA is the homodimer.

    • Biological materials

    Mutant

  • Pspac-csaA PubMed

    • References

    Reviews

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    Original publications

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