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tdk [2019-07-15 08:49:00]
function
biosynthesis of thymidine nucleotides
product
thymidine kinase (ATP:thymidine)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.4|Biosynthesis/ acquisition of pyrimidine nucleotides]Gene
Coordinates
3,802,405 → 3,802,992
The protein
Catalyzed reaction/ biological activity
ATP + thymidine = ADP + thymidine 5'-phosphate (according to Swiss-Prot)Protein family
thymidine kinase family (according to Swiss-Prot)Structure
[PDB|2JA1] (from B. cereus, 69% identity) [pubmed|17288553][SW|Localization]
cytoplasm (according to Swiss-Prot)Biological materials
Mutant
BKE37060 (Δ[gene|D97D4CFDF7A9A48A8764738ECFD42F1D3A900BE7|tdk]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGGCTTCGCTCCCCTCT, downstream forward: _UP4_TAGTCCAAAACATGGGTATABKK37060 (Δ[gene|D97D4CFDF7A9A48A8764738ECFD42F1D3A900BE7|tdk]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGGCTTCGCTCCCCTCT, downstream forward: _UP4_TAGTCCAAAACATGGGTATAReferences