lipoprotein, nutrient receptor, germination response to L-alanine
function
germination response to L-alanine
product
nutrient receptor
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.1|Germinant receptors][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|germination], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigF regulon], [SW|SigG regulon], [SW|SpoVT regulon]Gene
Coordinates on the chromosome (coding sequence)
3,393,293 -> 3,394,414
The protein
Protein family
gerABKC lipoprotein family (according to Swiss-Prot)[SW|Domains]
has an N-terminal signal sequence, lipidated on a Cys residue adjacent to the signal peptide [Pubmed|23335419][SW|Localization]
cell membrane (according to Swiss-Prot)outer surface of the inner spore membrane [Pubmed|23335419,21378181][SW|Interactions]
[SW|GerAA]-[SW|GerAB]-[SW|GerAC] (tentative receptor complex) [Pubmed|21378181,21378197][SW|GerAC] is part of the [SW|germinosome] in the spore inner membrane [Pubmed|21696470][SW|GerAC]-[protein|search|Lgt] to fix [SW|GerAC] to diacylglycerol in the membrane [Pubmed|15126458]Additional information
1,100 molecules are present per spore [Pubmed|23749970]Expression and Regulation
Operon
''[SW|gerAA]-[SW|gerAB]-[SW|gerAC]'' [Pubmed|3110007][SW|Sigma factor]
[protein|search|SigG] [Pubmed|15699190], [protein|search|SigF] [Pubmed|16497325]Regulation
expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG], [SW|SpoVT]) [Pubmed|16497325,15699190,8755877]expression level depends on sporulation conditions (medim composition, temperature) [Pubmed|22327596]Regulatory mechanism
[SW|SpoVT]: transcription repression [Pubmed|8755877]Additional information
1,100 molecules are present per spore [PubMed|23749970]References
3110007,17573930,12670969,2110996,15774895,16497325,16352818,8755877,21378181,21378197,21696470,15126458,22327596,22493018,23335419,23396907,22343299,16740944,23749970,24752279,24916603,11418573 
