ycsE [Tue Dec 13 2016 11:16:30 GMT+0100 (CET)]

5'-nucleotidase, dephosphorylation of the riboflavin precursor, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate

locus: BSU04040

pI: 4.00

mw: 27.00 kDa

function: dephosphorylation of the riboflavin precursor, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate

product: 5'-nucleotidase

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.2|Biosynthesis/ acquisition of riboflavin/ FAD]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of cofactors]

Gene

Coordinates on the chromosome (coding sequence): 456,068 -> 456,817

The protein

Catalyzed reaction/ biological activity

• dephosphorylation of the riboflavin precursor, 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate [Pubmed|26316208]

Protein family

• Cof family (according to Swiss-Prot)
• [SW|HAD superfamily] [Pubmed|26316208]

Structure

• [PDB|1NRW] ([SW|YwpJ], 31% identity)

Expression and Regulation

Operon

• ''ycsE'' [Pubmed|22383849]

References

• 16990279,27784292,26316208,22383849,25848029