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secG [2020-03-05 10:06:30]
preprotein translocase subunit
function
protein secretion
product
preprotein translocase subunit
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
3,455,093 → 3,455,323
The protein
Protein family
secG family (single member, according to UniProt)Structure
[PDB|3DL8] (structure of the ([protein|5350DC618130E013757EE667B9AFC5F2EC68EC08|SecY]-[protein|1007EA15FB7AF81A44400287DB68BCC497158ACF|SecE]-[protein|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|SecG])-[protein|AD7CD451B4AE638A719C91780339784A7FF0F248|SecA] complex) [Pubmed|18923516][SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]-[gene|C0B6520E74CE9F7EE3DEC8C0D83E0770F241C4E8|yvaK]-[gene|0472A4346ADA1DC41C9D00E8F3222A0EBB76DFA8|rnr]-[gene|D19519B5A776D6E8EC2BFE7A7D67469CA0A6459A|smpB]-[gene|5C12BB19B975F7FEBCFA119DAC66338C20FCECFA|ssrA]
description
[Pubmed|17369301]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|11544224], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]regulation
''[protein|search|yvaK]'': induced by stress ([protein|search|SigB]) [Pubmed|11544224]view in new tabBiological materials
Mutant
BKE33630 (Δ[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCCATACACCTCCAGAC, downstream forward: _UP4_TAGGGCAATGTTTGTATAAGBKK33630 (Δ[gene|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|secG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCCCATACACCTCCAGAC, downstream forward: _UP4_TAGGGCAATGTTTGTATAAGReferences
Reviews
Original publications
10074070,18923516,17369301,26747607