flhG [Mon Aug 31 2015 13:54:20 GMT+0200 (CEST)]

GTPase activating protein, activates FlhF, activates assembly of the flagellar C ring, control of flagellar basal body position

Locus: BSU16410

Isoelectric point: 9.65

Molecular weight: 33.00 kDa

Function: activation of FlhF

Product: GTPase activating protein

Essential: no

Synonyms: ylxH

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Exponential and early post-exponential lifestyles → Motility and chemotaxis → Motility and chemotaxis/ other
• Lifestyles → Exponential and early post-exponential lifestyles → Swarming
• Lifestyles → Coping with stress → Resistance against toxins/ antibiotics

Syns: ylxH

Categories containing this gene/protein

• motility and chemotaxis, resistance against toxins/ antibiotics

This gene is a member of the following regulons

• CodY regulon, DegU regulon, SigD regulon, Spo0A regulon

Gene

Phenotypes of a mutant

• susceptible to acriflavine and ethidium bromide, and severe growth inhibition as surfactin concentration increased up to 100ug/ml.

The protein

Catalyzed reaction/ biological activity

• binds FlhF and stimulates its GTPase activity PubMed
• controls the distance between the flagellar bodies PubMed

Protein family

• View classification (according to Swiss-Prot)

Structure

• 4RZ3 (from Geobacillus thermodenitrificans) PubMed
• 3SYN (complex with FlhF) PubMed

Localization

• cytoplasm (homogeneous) and flagellar basal body PubMed

Interactions

• forms homodimers PubMed
• FlhG-FlhF (FlhG binds the GTP-bound homodimer of FlhF) PubMed
• FlhG-(FliY-FliM)-FliG PubMed

Expression and Regulation

Operon

• part of the [[fla-che operon]]
• flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed
• ylxF-fliK-flgD-flgE-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB PubMed

Sigma factor

• flgB: SigA PubMed, SigD PubMed
• ylxF: SigD PubMed

Regulation

• see [[fla-che operon]]

Regulatory mechanism

• see [[fla-che operon]]

References

Reviews

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Original Publications

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