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ftsY [Thu Dec 22 2016 17:24:58 GMT+0100 (CET)]
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ftsY [Thu Dec 22 2016 17:24:58 GMT+0100 (CET)]

signal recognition particle
locus
BSU15950
pI
5.00
mw
36.00 kDa
function
protein secretion
product
signal recognition particle
essential
no
synonyms
srb

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|protein secretion], [SW|sporulation proteins], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|GerE regulon], [SW|SigK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,670,140 -> 1,671,129

    The protein

    Protein family

  • GTP-binding [protein|search|SRP] family (according to Swiss-Prot)
  • Structure

  • [PDB|2XXA] (complex [protein|search|Ffh]-[protein|search|FtsY]-[protein|search|Scr] RNA, from ''E. coli'') [Pubmed|21330537]
  • [SW|Localization]

  • cell membrane, peripheral, via N-terminal lipid-binding domain [Pubmed|19414018]
  • [SW|Interactions]

  • [protein|search|Ffh]-[protein|search|FtsY] in the [SW|signal recognition particle] [Pubmed|21330537]
  • [protein|search|SecY]-[protein|search|FtsY] [Pubmed|21255212]
  • Expression and Regulation

    Operon

  • ''[protein|search|rnc]-[protein|search|smc]-[protein|search|ftsY]'' [Pubmed|11021934]
  • ''[protein|search|ftsY]'' [Pubmed|11021934]
  • [SW|Sigma factor]

  • ''[protein|search|rnc]'': [protein|search|SigA] [Pubmed|11021934]
  • ''[protein|search|ftsY]'': [protein|search|SigK] [Pubmed|11021934]
  • Regulation

  • expressed during vegetative growth and during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|11021934]
  • Regulatory mechanism

  • [protein|search|GerE]: transcription activation [Pubmed|11021934]
  • References

    Reviews

  • 25212246,27890920
  • Original publications

  • 16705751,15995216,11021934,21330537,23563142,21255212,27355662,19414018