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qcrA [2018-11-23 15:45:40]
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qcrA [2018-11-23 15:45:40]

Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc1 complex
locus
BSU22560
pI
6.08
mw
18.59 kDa
protein length
167 aa Sequence Blast
gene length
501 bp Sequence Blast
function
respiration
product
menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)
essential
no
synonyms
bfcA,petC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    2,364,589 → 2,365,092

    The protein

    Protein family

  • accD/PCCB family (according to Swiss-Prot)

    • [SW|Cofactors]

  • Fe-S cluster [pubmed|29292548]

    • [SW|Localization]

  • cell membrane [Pubmed|23880299]
  • delivered to the membrane by the [protein|780FDF3DD260287428B397FFE7F44DDF1917381C|TatAY]-[protein|E60FC9C9B273DD6B07B7B95819525DE5F35113CE|TatCY] [SW|protein secretion] system, this depends on prior dusulfide bond formation and co-factor insertion [Pubmed|24652282,23256564]

    • Expression and Regulation

    Operons

    genes
    [gene|D4AF96C936093BA44E46FF92A3EDE437495B0923|qcrA]-[gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]-[gene|F2973C512AFB4B9F8FE0CCAF09646E60F886C013|qcrC]
    description
    [Pubmed|7592464]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|7592464], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD]: activation, [Pubmed|8631715], in [regulon|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD regulon]
  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|12850135], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • induced by oxygen limitation ([protein|search|ResD]) [Pubmed|8631715]
    • view in new tab

    Biological materials

    Mutant

  • BKE22560 (Δ[gene|D4AF96C936093BA44E46FF92A3EDE437495B0923|qcrA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTTCTCCCCCCTCTA, downstream forward: _UP4_GCAAAGCCTAAGGGGGAAGG
  • BKK22560 (Δ[gene|D4AF96C936093BA44E46FF92A3EDE437495B0923|qcrA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTTCTCCCCCCTCTA, downstream forward: _UP4_GCAAAGCCTAAGGGGGAAGG

    • References

    Reviews

  • 24140208

    • Original publications

  • 8631715,7592464,23880299,12850135,12107147,20817675,23256564,24652282,26239117,27503613