Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc1 complex
product
menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|respiration], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|CcpA regulon], [SW|ResD regulon]The protein
Protein family
accD/PCCB family (according to Swiss-Prot)[SW|Cofactors]
contains an iron-sulfur cluster[SW|Localization]
cell membrane [Pubmed|23880299]delivered to the membrane by the [SW|TatAY]-[SW|TatCY] [SW|protein secretion] system, this depends on prior dusulfide bond formation and co-factor insertion [Pubmed|24652282,23256564][SW|Interactions]
part of a [SW|respiratory supercomplex] [Pubmed|23880299][protein|search|QcrA]-[protein|search|QcrB]-[protein|search|QcrC] [Pubmed|23880299]Expression and Regulation
Operon
''[protein|search|qcrA]-[protein|search|qcrB]-[protein|search|qcrC]'' [Pubmed|7592464][SW|Sigma factor]
[protein|search|SigA] [Pubmed|7592464]Regulation
repressed by casamino acids [Pubmed|12107147]induced by oxygen limitation ([protein|search|ResD]) [Pubmed|8631715]repressed by glucose (5.5-fold) ([protein|search|CcpA]) [Pubmed|12850135]Regulatory mechanism
[protein|search|ResD]: transcription activation [Pubmed|8631715][protein|search|CcpA]: transcription repression [Pubmed|12850135][protein|search|AbrB]: transcription repression [Pubmed|20817675]References
Reviews
Original publications
8631715,7592464,23880299,12850135,12107147,20817675,23256564,24652282,26239117