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qcrA [2017-04-24 15:34:12]
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qcrA [2017-04-24 15:34:12]

Rieske factor, menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc1 complex
locus
BSU22560
pI
6.08
mw
18.59 kDa
protein length
167 aa Sequence Blast
gene length
501 bp Sequence Blast
function
respiration
product
menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)
essential
no
synonyms
bfcA, petC

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|CcpA regulon], [SW|ResD regulon]
  • Gene

    Coordinates
    2,364,589 → 2,365,092

    The protein

    Protein family

  • accD/PCCB family (according to Swiss-Prot)
  • [SW|Cofactors]

  • contains an iron-sulfur cluster
  • [SW|Localization]

  • cell membrane [Pubmed|23880299]
  • delivered to the membrane by the [protein|780FDF3DD260287428B397FFE7F44DDF1917381C|TatAY]-[protein|E60FC9C9B273DD6B07B7B95819525DE5F35113CE|TatCY] [SW|protein secretion] system, this depends on prior dusulfide bond formation and co-factor insertion [Pubmed|24652282,23256564]
  • Expression and Regulation

    Operons

    genes
    [gene|D4AF96C936093BA44E46FF92A3EDE437495B0923|qcrA]-[gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]-[gene|F2973C512AFB4B9F8FE0CCAF09646E60F886C013|qcrC]
    description
    [Pubmed|7592464]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|7592464], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulatory mechanism

  • [protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD]: activation, [Pubmed|8631715], in [regulon|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD regulon]
  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|12850135], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]
  • regulation

  • induced by oxygen limitation ([protein|search|ResD]) [Pubmed|8631715]
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    References

    Reviews

  • 24140208
  • Original publications

  • 8631715,7592464,23880299,12850135,12107147,20817675,23256564,24652282,26239117