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polX [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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polX [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

DNA polymerase X, involved in DNA repair, generates adaptive mutations by error-prone processing of A/P sites
Locus
BSU28590
Isoelectric point
5.31
Molecular weight
63.00 kDa
Function
DNA repair
Product
DNA polymerase X
Essential
no
E.C.
2.7.7.7
Synonyms
yshC

Genomic Context

      
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Categories containing this gene/protein

Categories containing this gene/protein

Gene

Coordinates on the chromosome (coding sequence)
2,923,314 -> 2,925,026

The protein

Catalyzed reaction/ biological activity

  • template-dependent DNA polymerase, fills single nucleotide gaps PubMed
  • has intrinsic 3'-5' exonuclease activity for resecting unannealed 3'-termini in gapped DNA substrates PubMed
  • has intrinsic apurinic/apyrimidinic (AP) endonuclease activity PubMed
  • Protein family

  • DNA polymerase X family
  • Interactions

  • monomeric PubMed
  • Labs working on this gene/protein

  • Margarita Salas, Madrid, Spain link
  • References

    Reviews

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    Original publications

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