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pdp [Mon Aug 31 2015 13:57:38 GMT+0200 (CEST)]
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pdp [Mon Aug 31 2015 13:57:38 GMT+0200 (CEST)]

pyrimidine nucleoside phosphorylase
locus
BSU39400
pI
4.77
mw
46.00 kDa
function
pyrimidine interconversion
product
pyrimidine nucleoside phosphorylase
essential
no
ec
2.4.2.2
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]

    • [SW|Categories] containing this gene/protein

  • [SW|utilization of nucleotides]

    • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|DeoR regulon]

    • The protein

    Catalyzed reaction/ biological activity

  • A pyrimidine nucleoside + phosphate = a pyrimidine base + alpha-D-ribose 1-phosphate (according to Swiss-Prot)

    • Protein family

  • thymidine/pyrimidine-nucleoside phosphorylase family (according to Swiss-Prot)

    • Structure

  • [PDB|1BRW] (Geobacillus stearothermophilus)

    • Expression and Regulation

    Operon

  • ''[protein|search|dra]-[protein|search|nupC]-[protein|search|pdp]'' [Pubmed|8550462]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|8550462]

    • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
  • induced by deoxynucleotides ([protein|search|DeoR]) [Pubmed|8550462]

    • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|10666464]
  • [protein|search|DeoR]: transcription repression [Pubmed|8550462]

    • References

  • 11065368,8550462,10074062,10666464