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smpB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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smpB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

tmRNA-binding protein
locus
BSU33600
pI
10.00
mw
17.00 kDa
function
trans-translation
product
tmRNA-binding protein
essential
no
synonyms
yvaI

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.12|Translation/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|sporulation/ other]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,451,248 -> 3,451,718

    Phenotypes of a mutant

  • impaired growth at high and low temperatures [Pubmed|15805528]
  • inactivation of ''[SW|smpB]'' reduces sporulation efficiency to 23% that of wild type cells; delayed entry into sporulation [Pubmed|26735940]
  • The protein

    Protein family

  • smpB family (according to Swiss-Prot)
  • Structure

  • [PDB|1P6V] (from ''Aquifex aeolicus'', 55% identity, complex with the tRNA domain of [SW|SsrA]) [Pubmed|12904796]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|SmpB]-[protein|search|SsrA]
  • Expression and Regulation

    Operon

  • ''[protein|search|secG]-[protein|search|yvaK]-[protein|search|rnr]-[protein|search|smpB]-[protein|search|ssrA]'' [Pubmed|17369301]
  • ''[protein|search|yvaK]-[protein|search|rnr]-[protein|search|smpB]-[protein|search|ssrA]'' [Pubmed|17369301]
  • ''[protein|search|smpB]-[protein|search|ssrA]'' [Pubmed|17369301]
  • Regulation

  • ''[protein|search|yvaK]'': [protein|search|SigB] [Pubmed|11544224]
  • Biological materials

    Mutant

  • MGNA-A494 (yvaI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/494 NBRP B. subtilis, Japan]
  • Labs working on this gene/protein

  • [SW|Chet Price], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
  • References

    Reviews

  • 12730326,10881189
  • Original publications

  • 18977770,11395451,17369301,10881189,15805528,12904796,26735940