SubtiBank SubtiBank
aseR [2018-06-07 19:42:07]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

aseR [2018-06-07 19:42:07]

transcriptional repressor of the ArsR family, of aseA and aseR
locus
BSU05330
pI
6.31
mw
12.95 kDa
protein length
111 aa Sequence Blast
gene length
333 bp Sequence Blast
function
regulation of As (III) efflux
product
transcriptional repressor (ArsR family)
essential
no
synonyms
ydeT
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.11|Resistance against toxic metals]

    • Gene

    Coordinates
    579,541 → 579,876

    The protein

    Protein family

  • [SW|ArsR family]

    • Effectors of protein activity

  • As(III) acts as molecular inducer [Pubmed|15948947]

    • Expression and Regulation

    Operons

    genes
    [gene|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]-[gene|C0E921ECAEE12DEC32A5DEE866762D6971360FA1|aseA]-[gene|6BA4A8575050B1BA45FF98E1F3B1F27F6C24A5E4|ydzS/1]-[gene|009BB4460A9374A8259DE7BD05724467198E0A90|ydzS/2]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|D169C58739F17EE0D341D015592FF07CBBE1B6E1|AseR]: repression, [Pubmed|15948947], in [regulon|D169C58739F17EE0D341D015592FF07CBBE1B6E1|AseR regulon]

    • regulation

  • induced by As(III) ([protein|D169C58739F17EE0D341D015592FF07CBBE1B6E1|AseR]) [Pubmed|15948947]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-C168 (ydeT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2166 NBRP B. subtilis, Japan]
  • BKE05330 (Δ[gene|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGCTCCTCCTTCCC, downstream forward: _UP4_TGTTGCCAGTAAGGAGGCAT
  • BKK05330 (Δ[gene|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAGCTCCTCCTTCCC, downstream forward: _UP4_TGTTGCCAGTAAGGAGGCAT

    • References

  • 15948947,16430705