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aseR
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aseR

transcriptional repressor of the ArsR family, of aseA and aseR
Locus
BSU_05330
Isoelectric point
6.31
Molecular weight
12.95 kDa
Protein length
111 aa Sequence Blast
Gene length
336 bp Sequence Blast
Function
regulation of As (III) efflux
Product
transcriptional repressor (ArsR family)
Essential
no
Synonyms
ydeT
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Regulation of gene expression → Transcription factors and their control → Transcription factors/ other
  • Lifestyles → Coping with stress → Resistance against toxic metals

    • Gene

    Coordinates
    579,541 → 579,876

    The protein

    Protein family

  • ArsR family

    • Domains

  • HTH arsR-type domain (aa 1-105) (according to UniProt)

    • Effectors of protein activity

  • As(III) acts as molecular inducer PubMed

    • Structure

  • 2OQG (from Rhodococcus sp., 27% identity)

    • Expression and Regulation

    Operons

    Genes
    aseR-aseA-ydzS/1-ydzS/2
    Description
    PubMed

    Regulatory mechanism

  • AseR: repression, PubMed, in AseR regulon

    • Regulation

  • induced by As(III) (AseR) PubMed
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    Biological materials

    Mutant

  • MGNA-C168 (ydeT::erm), available at the NBRP B. subtilis, Japan
  • BKE05330 (ΔaseR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGAGCTCCTCCTTCCC, downstream forward: _UP4_TGTTGCCAGTAAGGAGGCAT
  • BKK05330 (ΔaseR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATGAGCTCCTCCTTCCC, downstream forward: _UP4_TGTTGCCAGTAAGGAGGCAT

    • References

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