kduI [Mon Aug 31 2015 13:55:13 GMT+0200 (CEST)]

5-keto-4-deoxyuronate isomerase

locus: BSU22130

pI: 5.12

mw: 30.00 kDa

function: utilization of galacturonic acid

product: 5-keto-4-deoxyuronate isomerase

essential: no

ec: 5.3.1.17

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.15|Utilization of hexuronate]

[SW|Categories] containing this gene/protein

• [SW|utilization of specific carbon sources]

This gene is a member of the following [SW|regulons]

• [SW|CcpA regulon], [SW|KdgR regulon]

The protein

Catalyzed reaction/ biological activity

• 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate (according to Swiss-Prot)

Protein family

• PNP/MTAP phosphorylase family (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|kduI]-[protein|search|kduD]'' [Pubmed|17322190]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|17322190]

Regulation

• induced by galacturonate ([protein|search|KdgR]) [Pubmed|17322190]
• repressed by glucose ([protein|search|CcpA]) [Pubmed|17322190]

Regulatory mechanism

• [protein|search|KdgR]: transcription repression [Pubmed|17322190]
• [protein|search|CcpA]: transcription repression [Pubmed|17322190]

References

• 17322190