kduI [2017-8-11 16:0:3]

5-keto-4-deoxyuronate isomerase

locus: BSU22130

pI: 5.11

mw: 30.98 kDa

protein length: 275 aa

gene length: 825 bp

function: utilization of galacturonic acid

product: 5-keto-4-deoxyuronate isomerase

essential: no

ec: 5.3.1.17

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.15|Utilization of hexuronate]

Gene

Coordinates: 2,325,854 → 2,326,681

The protein

Catalyzed reaction/ biological activity

• 4-deoxy-L-threo-5-hexosulose uronate = 3-deoxy-D-glycero-2,5-hexodiulosonate (according to Swiss-Prot)

Protein family

• PNP/MTAP phosphorylase family (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|CFAEF60AD73F18C8DB5EF042210602B149D51152|kduI]-[gene|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD]
  description: [Pubmed|17322190]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|17322190], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  regulatory mechanism

  • [protein|891A32A19D1353BA566FF121BBCA7B986D31D129|KdgR]: repression, [Pubmed|17322190], in [regulon|891A32A19D1353BA566FF121BBCA7B986D31D129|KdgR regulon]
  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|17322190], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]

  regulation

  • induced by galacturonate ([protein|search|KdgR]) [Pubmed|17322190]

References

• 17322190