nudF [2017-8-11 16:0:3]

involved in isopentenol (isoprenoid) biosynthesis

locus: BSU23610

pI: 4.59

mw: 20.84 kDa

protein length: 185 aa

gene length: 555 bp

function: isoprenoid biosynthesis

product: unknown

essential: no

ec: 3.6.1.13

synonyms: yqkG

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.3|Biosynthesis of isoprenoids]

Gene

Coordinates: 2,458,509 → 2,459,066

The protein

Catalyzed reaction/ biological activity

• ADP-ribose + H₂O = AMP + D-ribose 5-phosphate (according to Swiss-Prot)

Protein family

• [SW|Nudix hydrolase], NudF subfamily (according to Swiss-Prot)

Structure

• [PDB|1V8I] (from ''Thermus thermophilus'', 38% identity) [Pubmed|15210687]

Expression and Regulation

Operons

• genes: [gene|CF38BE04F04919BB304789E9B3FE489385E468E6|nudF]-[gene|9D05B104000EED08FB62D6F362FC5E9C2A5354D9|yqxK]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-C410 (yqkG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2408 NBRP B. subtilis, Japan]

References

• 17693564,10542272,15210687