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safA [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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safA [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

morphogenetic protein associated with SpoVID, major organizer of the inner spore coat
locus
BSU27840
pI
5.75
mw
43.00 kDa
function
spore coat formation
product
morphogenetic protein
essential
no
synonyms
yrbA

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.8|Not yet assigned]
  • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigE regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,844,675 -> 2,845,838

    Phenotypes of a mutant

  • mis-assembly of the inner spore coat [Pubmed|22171814]
  • The protein

    [SW|Domains]

  • contains a N-acetylglucosamine-polymer-binding [SW|LysM domain] at the N-terminus [Pubmed|18430080]
  • [SW|Localization]

  • inner spore coat [Pubmed|23202530]
  • [SW|Interactions]

  • [SW|SpoVID]-[protein|search|SafA] [Pubmed|19702880,22262582]
  • [SW|SpoIVA]-[protein|search|SafA] [Pubmed|19702880,22262582]
  • Expression and Regulation

    Operon

  • ''[protein|search|safA]-[protein|search|coxA]'' [Pubmed|10438771]
  • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|10438771]
  • Regulation

  • expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|10438771]
  • Biological materials

    Mutant

  • 1S126 ( ''safA''::''erm''), [Pubmed|16751597], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S126&Search=1S126 BGSC]
  • 1S117 ( ''safA''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S117&Search=1S117 BGSC]
  • Labs working on this gene/protein

  • [SW|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]
  • [SW|Charles Moran], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
  • References

    Reviews

  • 18430080,22192522,23202530
  • Original publications

  • 10438771,16950916,11222602,11325931,20451384,10714986,22171814,22262582,23811766,25259857,26187959