ypbH [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

putative adaptor protein for ClpC-ClpP

locus: BSU22970

pI: 4.10

mw: 22.00 kDa

function: unknown

product: putative adaptor protein

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]

[SW|Categories] containing this gene/protein

• [SW|proteolysis]

Gene

Coordinates on the chromosome (coding sequence): 2,403,506 -> 2,404,090

Phenotypes of a mutant

• deletion reduces sporulation to 20%, overexpression abolishes sporulation [Pubmed|11914365]

The protein

Paralogous protein(s)

• [protein|search|MecA]

Structure

• [http://www.proteopedia.org/wiki/index.php/3jto 3JTO] (C-terminal domain) [Pubmed|19801546]

[SW|Interactions]

• [protein|search|YpbH]-[protein|search|ClpC] [Pubmed|11914365]

Expression and Regulation

Regulation

• low expression, enhanced in stat phase in LB or competence but not in sporulation medium [Pubmed|11914365]

Biological materials

Mutant

• GP812 (spc), GP814 (spc) both available in the [SW|Stülke] lab

References

Reviews

• 19609260,23375660

Original Publications

• 11914365,19801546