yjmD

galactitol-1-phosphate dehydrogenase

Locus: BSU_12330

Isoelectric point: 6.11

Molecular weight: 36.61 kDa

Protein length: 339 aa

Gene length: 1020 bp

Function: utilization of dulcitol

Product: galactitol-1-phosphate dehydrogenase

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of hexuronate
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

Gene

Coordinates: 1,304,442 → 1,305,461

The protein

Protein family

• zinc-containing alcohol dehydrogenase family (according to UniProt)

Structure

• 4ILK (from E. coli, 40% identity)

Expression and Regulation

Operons

• Genes: yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigE: sigma factor, PubMed, in SigE regulon

  Regulatory mechanism

  • ExuR: repression, in the absence of inducer, in ExuR regulon
  • CcpA: repression, PubMed PubMed, in CcpA regulon

  Regulation

  • induced by galacturonate (ExuR) PubMed

• Genes: uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • ExuR: repression, in the absence of inducer, in ExuR regulon
  • CcpA: repression, PubMed PubMed, in CcpA regulon

  Regulation

  • induced by galacturonate (ExuR) PubMed

Biological materials

Mutant

• MGNA-A368 (yjmD::erm), available at the NBRP B. subtilis, Japan
• BKE12330 (ΔyjmD::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACTTGAACCGCTTTCATTT, downstream forward: _UP4_TAAATGACTGAATCCGGAGG
• BKK12330 (ΔyjmD::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACTTGAACCGCTTTCATTT, downstream forward: _UP4_TAAATGACTGAATCCGGAGG

References

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