flgC

flagellar basal-body rod protein, required for the assembly of the flagellar hook and filament

Locus: BSU_16190

Isoelectric point: 5.73

Molecular weight: 16.12 kDa

Protein length: 150 aa

Gene length: 453 bp

Function: movement and chemotaxis

Product: flagellar basal-body rod protein

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Exponential and early post-exponential lifestyles → Motility and chemotaxis → Flagellar proteins
• Groups of genes → Secreted proteins

Gene

Coordinates: 1,691,667 → 1,692,119

Phenotypes of a mutant

• defective in swarming and flagellar assembly PubMed

The protein

Protein family

• Flagella basal body rod proteins family (according to UniProt)

Localization

• bacterial flagellum basal body (according to Swiss-Prot), extracellular (no signal peptide) PubMed

Expression and Regulation

Operons

• Genes: flgB-flgC-fliE-fliF-fliG-fliH-fliI-fliJ-ylxF-fliK-flgD-flgE-swrD-fliL-fliM-fliY-cheY-fliZ-fliP-fliQ-fliR-flhB-flhA-flhF-flhG-cheB-cheA-cheW-cheC-cheD-sigD-swrB
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigD: sigma factor, PubMed, in SigD regulon

  Regulatory mechanism

  • Spo0A: repression, in Spo0A regulon
  • SwrA: activation, in SwrA regulon
  • CodY: repression, in CodY regulon
  • DegU: repression, in DegU regulon

  Regulation

  • expression during spore germination is strongly reduced under conditions of osmotic stress PubMed

Biological materials

Mutant

• BKE16190 (ΔflgC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATTTAAGCTATGAAAAGCTG, downstream forward: _UP4_GAAATCGGAAAGTAGGTGAA
• BKK16190 (ΔflgC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_ATTTAAGCTATGAAAAGCTG, downstream forward: _UP4_GAAATCGGAAAGTAGGTGAA

References

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