atpB

ATP synthase, part of the Fo complex (subunit a)

Locus: BSU_36870

Isoelectric point: 9.36

Molecular weight: 26.90 kDa

Protein length: 244 aa

Gene length: 735 bp

Function: ATP synthesis

Product: ATP synthase (subunit a))

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Metabolism → Electron transport and ATP synthesis → ATP synthesis → ATPase
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,786,878 → 3,787,612

The protein

Catalyzed reaction/ biological activity

• ATP synthesis see a video

Protein family

• ATPase A chain family (single member, according to UniProt)

Effectors of protein activity

• ATPase activity is inhibited upon binding of Mg-ADP to AtpD PubMed

Structure

• 5T4O (ATPase from E. coli, 31% identity) PubMed

Localization

• membrane PubMed

Expression and Regulation

Operons

• Genes: atpI-atpB-atpE-atpF-atpH-atpA-atpG-atpD-atpC
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response

  Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed
  • the mRNA is processed between atpI and atpB by RNase Y, this requires the YmcA-YlbF-YaaT complex PubMed

Biological materials

Mutant

• BKE36870 (ΔatpB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAAGGGTTTTCACCTCTCT, downstream forward: _UP4_TAAAACATTATATCCAAACG
• BKK36870 (ΔatpB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAAGGGTTTTCACCTCTCT, downstream forward: _UP4_TAAAACATTATATCCAAACG

References

Reviews

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Original publications

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