opuCC [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

glycine betaine/carnitine/choline ABC transporter (binding protein)

locus: BSU33810

pI: 5.69

mw: 33.00 kDa

function: compatible solute transport

product: glycine betaine/carnitine/choline ABC transporter (binding protein)

essential: no

synonyms: yvbC

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.4|Uptake of compatible solutes for osmoprotection]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

syns: yvbC

[SW|Categories] containing this gene/protein

• [SW|ABC transporters], [SW|coping with hyper-osmotic stress], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|OpcR regulon], [SW|RemA regulon]

The protein

Paralogous protein(s)

• [SW|OpuBC]

Structure

• [PDB|3PPN] [Pubmed|21366542]

[SW|Localization]

• associated to the membrane (via [SW|OpuCB]-[SW|OpuCD]) [Pubmed|10092453]
• lipoprotein [Pubmed|10216873]

[SW|Interactions]

• [SW|OpuCA]-([SW|OpuCB]-[SW|OpuCD])-[SW|OpuCC] [Pubmed|10092453]

Expression and Regulation

Operon

• ''[SW|opuCA]-[SW|opuCB]-[SW|opuCC]-[SW|opuCD]'' [Pubmed|10216873]

[SW|Sigma factor]

• induced by salt stress [Pubmed|23960087,10216873]
• repressed by choline ([protein|search|OpcR]) [Pubmed|23960087]

Regulatory mechanism

• [protein|search|OpcR]: transcription repression [Pubmed|23960087]
• [protein|search|RemA]: transcription activation [Pubmed|23646920]

References

• 10092453,9925583,10216873,21296969,21366542,23960087,23646920