opuCC

glycine betaine/carnitine/choline/arsenobetaine/arsenocholine ABC transporter (binding protein)

Locus: BSU_33810

Isoelectric point: 5.69

Molecular weight: 33.80 kDa

Protein length: 303 aa

Gene length: 912 bp

Function: compatible solute transport

Product: glycine betaine/carnitine/choline/arsenobetaine/arsenocholine ABC transporter (binding protein)

Essential: no

Synonyms: yvbC

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → ABC transporters → Importers → Uptake of compatible solutes for osmoprotection
• Lifestyles → Coping with stress → Coping with hyper-osmotic stress
• Groups of genes → Membrane proteins

Gene

Coordinates: 3,468,253 → 3,469,164

The protein

Catalyzed reaction/ biological activity

• uptake of glycine betaine, arsenocholine and arsenobetaine PubMed

Protein family

• OsmX family (with OpuBC, according to UniProt)

Paralogous protein(s)

• OpuBC

Structure

• 3PPN PubMed

Localization

• associated to the membrane (via OpuCB-OpuCD) PubMed
• lipoprotein PubMed

Expression and Regulation

Operons

• Genes: opuCA-opuCB-opuCC-opuCD
  Description: PubMed

  Regulatory mechanism

  • OpcR: repression, (sterical interference with RNA polymerase access) PubMed, in OpcR regulon
  • RemA: activation, PubMed, in RemA regulon
  • YlxR: regulation, PubMed, in YlxR regulon

  Regulation

  • induced by salt stress PubMed
  • induced in the absence of YlxR PubMed

Biological materials

Mutant

• BKE33810 (ΔopuCC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TGTCATTTTCAACAGTGCCA, downstream forward: _UP4_GACTAAGAAAAGAGGTGGAT
• BKK33810 (ΔopuCC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TGTCATTTTCAACAGTGCCA, downstream forward: _UP4_GACTAAGAAAAGAGGTGGAT

References

Reviews

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Original publications

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