SubtiBank SubtiBank
tenI
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tenI

thiazole tautomerase
Locus
BSU_11660
Isoelectric point
8.13
Molecular weight
22.78 kDa
Protein length
205 aa Sequence Blast
Gene length
618 bp Sequence Blast
Function
biosynthesis of thiamine
Product
thiazole tautomerase
Essential
no
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,243,134 → 1,243,751

The protein

Catalyzed reaction/ biological activity

  • 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate --> 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (according to UniProt)
  • Protein family

  • thiazole tautomerase family (single member, according to UniProt)
  • Paralogous protein(s)

    Structure

    Expression and Regulation

    Operons

    Description

    Regulatory mechanism

    Regulation

  • repressed by thiamine (Thi-box) PubMed
  • the Thi-box RNA is degraded by RNase Y PubMed
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    Biological materials

    Mutant

  • BKE11660 (ΔtenI::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CGCTAGCTCTTCTACCGGCT, downstream forward: _UP4_TCCCGCAAGCTAAAGGAGAT
  • BKK11660 (ΔtenI::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CGCTAGCTCTTCTACCGGCT, downstream forward: _UP4_TCCCGCAAGCTAAAGGAGAT
  • References

    Reviews

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    Original publications

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