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pucA [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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pucA [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

xanthine dehydrogenase
locus
BSU32510
pI
6.36
mw
36.00 kDa
function
purine utilization
product
xanthine dehydrogenase
essential
no
synonyms
yurF

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of nucleotides]
  • This gene is a member of the following [SW|regulons]

  • [SW|PucR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,339,945 -> 3,340,937

    The protein

    Catalyzed reaction/ biological activity

  • Xanthine + NAD+ + H2O = urate + NADH (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|pucA]-[protein|search|pucB]-[protein|search|pucC]-[protein|search|pucD]-[protein|search|pucE]'' [Pubmed|12823818]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|12029039]
  • Regulation

  • induced in the presence of purine nucleotides (effector: allantoin) ([protein|search|PucR]) [Pubmed|12029039]
  • Regulatory mechanism

  • [protein|search|PucR]: transcription activaton [Pubmed|12029039]
  • References

  • 11344136,12029039,12823818