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refZ [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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refZ [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

regulator of FtsZ (TetR family), facilitates switch from medial to polar FtsZ ring placement during sporulation
locus
BSU29630
pI
6.00
mw
24.00 kDa
function
relocalization of the FtsZ ring
product
regulator of FtsZ
essential
no
synonyms
yttP

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|cell division], [SW|sporulation/ other]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|PhoP regulon], [SW|Spo0A regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,032,417 -> 3,033,040

    The protein

    Catalyzed reaction/ biological activity

  • facilitates switch from medial to polar [protein|search|FtsZ] ring placement during [SW|sporulation] [Pubmed|22730127]
  • [SW|Domains]

  • TetR-like DNA-binding helix-turn-helix domain at the N-terminus [Pubmed|22730127]
  • [SW|Localization]

  • polar foci [Pubmed|22730127]
  • [SW|Interactions]

  • [protein|search|RefZ]-[protein|search|FtsZ] [Pubmed|22730127]
  • Expression and Regulation

    Operon

  • ''refZ'' [Pubmed|22383849]
  • Regulation

  • repressed by glucose (3.1-fold) ([protein|search|CcpA]) [Pubmed|12850135]
  • induced early during [SW|sporulation] ([SW|Spo0A]) [Pubmed|14651647]
  • expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|14762014]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|12850135]
  • [SW|Spo0A]: transcription activation [Pubmed|14651647]
  • [protein|search|PhoP]: transcription activation [Pubmed|14762014]
  • References

    Reviews

  • 24006471
  • Original publications

  • 14651647,14762014,12850135,22730127,22383849,26360512