regulator of FtsZ (TetR family), facilitates switch from medial to polar FtsZ ring placement during sporulation
function
relocalization of the FtsZ ring
product
regulator of FtsZ
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|cell division], [SW|sporulation/ other]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|PhoP regulon], [SW|Spo0A regulon]Gene
Coordinates on the chromosome (coding sequence)
3,032,417 -> 3,033,040
The protein
Catalyzed reaction/ biological activity
facilitates switch from medial to polar [protein|search|FtsZ] ring placement during [SW|sporulation] [Pubmed|22730127][SW|Domains]
TetR-like DNA-binding helix-turn-helix domain at the N-terminus [Pubmed|22730127][SW|Localization]
polar foci [Pubmed|22730127][SW|Interactions]
[protein|search|RefZ]-[protein|search|FtsZ] [Pubmed|22730127]Expression and Regulation
Operon
''refZ'' [Pubmed|22383849]Regulation
repressed by glucose (3.1-fold) ([protein|search|CcpA]) [Pubmed|12850135]induced early during [SW|sporulation] ([SW|Spo0A]) [Pubmed|14651647]expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|14762014]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|12850135][SW|Spo0A]: transcription activation [Pubmed|14651647][protein|search|PhoP]: transcription activation [Pubmed|14762014]References
Reviews
Original publications
14651647,14762014,12850135,22730127,22383849,26360512