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reoM
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reoM

effector protein of MurAA degradation by ClpC-ClpP
Locus
BSU_27400
Isoelectric point
4.73
Molecular weight
10.10 kDa
Protein length
88 aa Sequence Blast
Gene length
267 bp Sequence Blast
Function
control of peptidoglycan biosynthesis
Product
regulator of MurAA degradation
Essential
no
Synonyms
yrzL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall/ other

    • Gene

    Coordinates
    2,797,823 → 2,798,089

    Phenotypes of a mutant

  • accumulation of MurAA due to reduced degradation by ClpC-ClpP PubMed

    • The protein

    Protein family

  • UPF0297 family (single member, according to UniProt)

    • Structure

  • 5US5 (from Enterococcus faecalis, 66% identity) PubMed
  • 6TIF (from Listeria monocytogenes, 68% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    reoM-yrrK-yrzB
    Description
    PubMed
    view in new tab

    Genes
    alaS-reoM-yrrK-yrzB
    Description
    PubMed

    Regulatory mechanism

  • T-box: antitermination, in T-box

    • Regulation

  • induced by alanine limitation (T-box) PubMed
    • view in new tab

    Biological materials

    Mutant

  • BKE27400 (ΔreoM::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACCGTTTTGCACCTCTTTC, downstream forward: _UP4_CAGCATAAAGAGGCGTAAAT
  • BKK27400 (ΔreoM::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CACCGTTTTGCACCTCTTTC, downstream forward: _UP4_CAGCATAAAGAGGCGTAAAT

    • References

    Research papers

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