SubtiBank SubtiBank
yvcN
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yvcN

unknown
locus
BSU_34730
pI
5.58
mw
28.68 kDa
protein length
254 aa Sequence Blast
gene length
765 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • Gene

    Coordinates
    3,568,527 → 3,569,291

    The protein

    Protein family

  • [SW|Acetyltransferase family] (according to UniProt)

    • Structure

  • [PDB|3LNB] (from ''B. anthracis'', 35% identity, 68% similarity)

    • Additional information

  • The gene is annotated in KEGG as an ortholog of EC 2.3.1.5 and is marked in Swiss-Prot as “uncharacterized acetyltransferase” (EC 2.3.1.-). No EC annotation is available in MetaCyc.No literature/ experimental evidence supporting the annotation is available. [Pubmed|19935659]

    • Expression and Regulation

    Operons

    genes
    [gene|0C40455EB53D25363FC3EB0E84502A76520F5F91|nahA]-[gene|EB12C6B4F36B57BF0C59CE048CBAE18734C78D35|yvcJ]-[gene|7150BABA5086D5E2EB8102E4901A216F43576282|glmR]-[gene|1986DB3078FBA16D6ACCD70EEAC95C46564D0958|whiA]-[gene|A269774F2FDC94F93BA5F1360FFFE754B50383AD|crh]-[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]
    description
    [Pubmed|9237995]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|16272399], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]

    • regulation

  • constitutive expression at both protein and RNA levels [Pubmed|24097947,22383849]

    • additional information

  • A [protein|search|ncRNA] is predicted between '[protein|search|yvcI]' and '[protein|search|trxB]' [PubMed|20525796]
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    Biological materials

    Mutant

  • MGNA-B638 (yvcN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1637 NBRP B. subtilis, Japan]
  • BKE34730 (Δ[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE34730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAGAAAGTCACTCATTTTTA, downstream forward: _UP4_TAACGTGAAAAGCTTGCAGG
  • BKK34730 (Δ[gene|C521BEE1EEEA7AD283A3C47C34301A8603CD9188|yvcN]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK34730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAGAAAGTCACTCATTTTTA, downstream forward: _UP4_TAACGTGAAAAGCTTGCAGG

    • two-hybrid system

  • ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in [SW|Jörg Stülke]'s lab

    • References

  • 9237995,16272399