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hepS
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hepS

heptaprenyl diphosphate synthase component I
Locus
BSU_22760
Isoelectric point
6.27
Molecular weight
28.97 kDa
Protein length
251 aa Sequence Blast
Gene length
756 bp Sequence Blast
Function
menaquinone biosynthesis
Product
heptaprenyl diphosphate synthase component I (together with HepT)
Essential
no
E.C.
2.5.1.30
Synonyms
gerCA,hepA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of menaquinone

    • Gene

    Coordinates
    2,383,615 → 2,384,370

    Phenotypes of a mutant

  • essential PubMed, non-essential according to PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate --> all-trans-heptaprenyl diphosphate + 4 diphosphate (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    hepS-menH-hepT-ndk
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE22760 (ΔhepS::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAAAATATCACCCTTGTCC, downstream forward: _UP4_TAAACCATTATGCAGGACTC
  • BKK22760 (ΔhepS::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAAAATATCACCCTTGTCC, downstream forward: _UP4_TAAACCATTATGCAGGACTC

    • References

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