probably ABC transporter for melibiose (binding protein)
function
probably melibiose uptake
product
ABC transporter (binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.1|Uptake of carbon sources][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.21|Utilization of melibiose][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|utilization of specific carbon sources], [SW|membrane proteins], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon]Gene
Coordinates on the chromosome (coding sequence)
3,097,850 -> 3,099,130
The protein
Structure
[PDB|4R6H][SW|Localization]
extracellular (signal peptide), associated to the cell membrane (via [protein|search|AmyC]-[protein|search|AmyD]) [Pubmed|18957862,10092453][SW|Interactions]
([protein|search|AmyC]-[protein|search|AmyD])-[protein|search|MsmE] [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|msmR]-[protein|search|msmE]-[protein|search|amyD]-[protein|search|amyC]-[protein|search|melA]'' [Pubmed|22383849]''[protein|search|msmE]-[protein|search|amyD]-[protein|search|amyC]-[protein|search|melA]'' [Pubmed|22383849][SW|Sigma factor]
''[protein|search|msmR]'': [protein|search|SigA] [Pubmed|22900538]Regulation
[protein|search|MsmR]repressed by glucose ([protein|search|CcpA]) [Pubmed|22900538]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|22900538]References
10092453,22383849,22900538,18957862 
