yhjQ

copper storage protein

Locus: BSU_10600

Isoelectric point: 4.90

Molecular weight: 11.70 kDa

Protein length: 108 aa

Gene length: 327 bp

Function: prevention of copper toxicity

Product: copper storage protein

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Homeostasis → Trace metal homeostasis (Cu, Zn, Ni, Mn, Mo) → Copper
• Lifestyles → Sporulation → Sporulation proteins → Newly identified sporulation proteins (based on transcription profiling)

Gene

Coordinates: 1,135,255 → 1,135,581

The protein

Catalyzed reaction/ biological activity

• binding of Cu(I) ions (up to 80 ions per tetramer) to prevent copper toxicity PubMed

Structure

• 5FIG PubMed

Expression and Regulation

Operons

• Genes: yhjR-yhjQ
  Description: PubMed

  Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon
  • SigK: sigma factor, PubMed, in SigK regulon

  Regulatory mechanism

  • GerE: repression, PubMed, in GerE regulon

  Regulation

  • expressed during sporulation in the mother cell (SigE, SigK, GerE) PubMed

Biological materials

Mutant

• MGNA-B288 (yhjQ::erm), available at the NBRP B. subtilis, Japan
• BKE10600 (ΔyhjQ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGGTTGATTCCCCCTGTA, downstream forward: _UP4_TAAAAAAGAGGGTTCAAAAA
• BKK10600 (ΔyhjQ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGGTTGATTCCCCCTGTA, downstream forward: _UP4_TAAAAAAGAGGGTTCAAAAA

References

Reviews

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Original publications

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