transcriptional activator of the proline utilization operon putB-putC-putP
function
regulation of proline utilization
product
transcriptional activator (PucR family)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.2|Utilization of proline][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|utilization of amino acids]Gene
Phenotypes of a mutant
no growth with proline as single source of carbon or nitrogen [Pubmed|21840319]The protein
Catalyzed reaction/ biological activity
transcription activation of the proline utilization operon ''[protein|search|putB]-[protein|search|putC]-[protein|search|putP]'' in the presence of proline [Pubmed|21840319,21964733]Protein family
[SW|PucR family][SW|Cofactors]
proline acts as co-activator [Pubmed|21840319]Effectors of protein activity
proline activates PutR [Pubmed|21840319]Expression and Regulation
Operon
''[protein|search|putR]'' [Pubmed|21840319][SW|Sigma factor]
[protein|search|SigA] [Pubmed|21964733]Regulation
constitutively expressed [Pubmed|21840319,21964733]References
21840319,21964733,22139509