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iolE [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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iolE [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

2-keto-myo-inositol dehydratase, dehydration of 2-keto-myo-inositol (2nd reaction)
Locus
BSU39720
Isoelectric point
5.21
Molecular weight
33.00 kDa
Function
myo-inositol catabolism
Product
2-keto-myo-inositol dehydratase,
dehydration of 2-keto-myo-inositol (2nd reaction)
Essential
no
E.C.
4.2.1.44
Synonyms
yxdE

Genomic Context

      
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Categories containing this gene/protein

Categories containing this gene/protein

This gene is a member of the following regulons

Gene

Coordinates on the chromosome (coding sequence)
4,078,173 -> 4,079,066

The protein

Catalyzed reaction/ biological activity

  • 2,4,6/3,5-pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione + H2O (according to Swiss-Prot)
  • Protein family

  • iolE/mocC family (according to Swiss-Prot)
  • Structure

  • 3CNY (from Lactobacillus plantarum wcfs1 mutant, 63% identity, 78% similarity)
  • Expression and Regulation

    Operon

    Sigma factor

    Regulation

  • repressed by glucose (CcpA) PubMed
  • induced by inositol (IolR) PubMed
  • Regulatory mechanism

  • IolR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • Labs working on this gene/protein

  • Yasutaro Fujita, University of Fukuyama, Japan
  • [[Ken-ichi Yoshida]], Kobe University, Japan
  • References

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