SubtiBank SubtiBank
bceR [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

bceR [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

two-component response regulator (OmpR family), regulation of bceA-bceB in response to external (bacitracin, plectasin, mersacidin and actagardine) and internal (SdpC, SkfA) antimicrobial peptides
locus
BSU30400
pI
5.00
mw
26.00 kDa
function
resistance against toxic peptides
product
two-component response regulator (OmpR family)
essential
no
synonyms
ytsA

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.1|Two-component system response regulators]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.2|Phosphorylation on an Asp residue]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription factors and their control], [SW|resistance against toxins/ antibiotics], [SW|phosphoproteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,113,187 -> 3,113,882

    The protein

    Protein family

  • [SW|OmpR family]
  • Modification

  • phosphorylated by [protein|search|BceS] on an Asp residue
  • Structure

  • [PDB|1KGS] (DrrD from ''Thermotoga maritima '', 32% identity) [Pubmed|11839301]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|BceS]-[protein|search|BceR] [Pubmed|25118291]
  • Expression and Regulation

    Operon

  • ''[protein|search|bceR]-[protein|search|bceS]'' [Pubmed|12399481]
  • Biological materials

    Mutant

  • MGNA-A133 (ytsA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/133 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 27344142
  • Original publications

  • 10094672,18394148,12890034,14651641,21283517,20606066,17905982,25118291,22964256,21078927,26199330,26364265,11839301