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bceR [2019-08-28 12:30:16]
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bceR [2019-08-28 12:30:16]

two-component response regulator (OmpR family), regulation of bceA-bceB in response to external (bacitracin, plectasin, mersacidin and actagardine) and internal (SdpC, SkfA) antimicrobial peptides
Locus
BSU_30400
Isoelectric point
5.29
Molecular weight
26.72 kDa
Protein length
231 aa Sequence Blast
Gene length
696 bp Sequence Blast
Function
resistance against toxic peptides
Product
two-component response regulator (OmpR family)
Essential
no
Synonyms
ytsA

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,113,187 → 3,113,882

The protein

Protein family

Modification

  • phosphorylated by BceS on an Asp residue
  • Structure

  • 1KGS (DrrD from Thermotoga maritima , 32% identity) PubMed
  • Localization

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    Biological materials

    Mutant

  • MGNA-A133 (ytsA::erm), available at the NBRP B. subtilis, Japan
  • BKE30400 (ΔbceR::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAATCGACTCACCGCACTTT, downstream forward: _UP4_ATCGCGAAGGAAGAGGACAA
  • BKK30400 (ΔbceR::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAATCGACTCACCGCACTTT, downstream forward: _UP4_ATCGCGAAGGAAGAGGACAA
  • References

    Reviews

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    Original publications

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