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rbsK [Mon Aug 31 2015 13:57:08 GMT+0200 (CEST)]
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rbsK [Mon Aug 31 2015 13:57:08 GMT+0200 (CEST)]

ribokinase
locus
BSU35920
pI
4.61
mw
30.00 kDa
function
ribose utilization
product
ribokinase
essential
no
ec
2.7.1.15
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.4|Utilization of ribose]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|CcpA regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP + D-ribose = ADP + D-ribose 5-phosphate (according to Swiss-Prot)
  • Protein family

  • carbohydrate kinase pfkB family (according to Swiss-Prot)
  • Structure

  • [PDB|1VM7] (the enzyme of ''Thermotoga maritima'', 38% identity)
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|rbsR]-[protein|search|rbsK]-[protein|search|rbsD]-[protein|search|rbsA]-[protein|search|rbsC]-[protein|search|rbsB]'' [Pubmed|7921236]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|7511775]
  • Regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|7921236]
  • expressed upon transition into the stationary phase ([protein|search|AbrB]) [Pubmed|7592460]
  • Regulatory mechanism

  • [protein|search|CcpA]: transcription repression [Pubmed|7921236]
  • [protein|search|AbrB]: transcription activation [Pubmed|7592460]
  • References

  • 16872404,7511775,7592460,7921236