glnK [2017-8-11 16:0:3]

two-component sensor kinase, regulation of the glsA-glnT operon

locus: BSU02440

pI: 5.73

mw: 44.00 kDa

protein length: 387 aa

gene length: 1161 bp

function: regulation of the glsA-glnT operon

product: two-component sensor kinase

essential: no

synonyms: ycbA, yzgA

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

Gene

Coordinates: 265,476 → 266,708

The protein

Catalyzed reaction/ biological activity

• autophosphorylation, phosphorylation of [protein|4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B|GlnL]

[SW|Domains]

• four transmembrane segments, C-terminal histidine phosphotransferase domain

Modification

• autophosphorylation on a His residue

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|C18B886D06879C64B64606371E85A7D4D22DCFAC|glnK]-[gene|4E6EA2EABBDAA427E8F9EE1AE1800AF8657CF18B|glnL]
  description: [pubmed|22383849]

References

• 10094672,15995196