glnK [Tue Jan 05 2016 13:39:25 GMT+0100 (CET)]

two-component sensor kinase, regulation of the glsA-glnT operon

locus: BSU02440

pI: 5.00

mw: 43.00 kDa

function: regulation of the glsA-glnT operon

product: two-component sensor kinase

essential: no

synonyms: ycbA, yzgA

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis/ acquisition of amino acids], [SW|utilization of amino acids], [SW|protein modification], [SW|transcription factors and their control], [SW|membrane proteins], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence): 265,476 -> 266,708

The protein

Catalyzed reaction/ biological activity

• autophosphorylation, phosphorylation of [protein|search|GlnL]

[SW|Domains]

• four transmembrane segments, C-terminal histidine phosphotransferase domain

Modification

• autophosphorylation on a His residue

Structure

• [PDB|4R25] [Pubmed|25691471]
• [PDB|4RX6] (Complex with ATP) [Pubmed|25691471]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

[SW|Interactions]

• [protein|search|GlnK]-[protein|search|GlnL]

References

• 10094672,15995196,25691471