yitS

fatty acid binding protein

Locus: BSU_11110

Isoelectric point: 5.63

Molecular weight: 31.12 kDa

Protein length: 283 aa

Gene length: 852 bp

Function: phosphorylation of fatty acids

Product: fatty acid binding protein

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Metabolism → Lipid metabolism → Biosynthesis of lipids → Biosynthesis of phospholipids

Gene

Coordinates: 1,187,700 → 1,188,551

The protein

Catalyzed reaction/ biological activity

• binds and presents fatty acids for phosphorylation to FakA (based on findings for homologous proteins from Staphylococcus aureus) PubMed

Paralogous protein(s)

• DegV

Domains

• DegV domain (aa 3-282) (according to UniProt)

Structure

• 1PZX (Geobacillus stearothermophilus)

Expression and Regulation

Operons

• Genes: yitS
  Description: PubMed

Biological materials

Mutant

• MGNA-B196 (yitS::erm), available at the NBRP B. subtilis, Japan
• BKE11110 (ΔyitS::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTGCTTCCCTTCTTTC, downstream forward: _UP4_TGAGCAAACAAAAACAGTCA
• BKK11110 (ΔyitS::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTGCTTCCCTTCTTTC, downstream forward: _UP4_TGAGCAAACAAAAACAGTCA

References

Research papers

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