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aseA [2017-8-11 16:0:3]
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aseA [2017-8-11 16:0:3]

As(III) efflux pump
locus
BSU05340
pI
8.97
mw
47.16 kDa
protein length
435 aa Sequence Blast
gene length
1305 bp Sequence Blast
function
resistance to arsenite
product
As(III) efflux pump
essential
no
synonyms
ydfA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.11|Resistance against toxic metals]

    • Gene

    Coordinates
    579,889 → 581,196

    The protein

    Paralogous protein(s)

  • [protein|EB8E3F88BC1ED2BAD5A98D609EDAA002261150A5|YwrK]

    • Expression and Regulation

    Operons

    genes
    [gene|D169C58739F17EE0D341D015592FF07CBBE1B6E1|aseR]-[gene|C0E921ECAEE12DEC32A5DEE866762D6971360FA1|aseA]-[gene|6BA4A8575050B1BA45FF98E1F3B1F27F6C24A5E4|ydzS/1]-[gene|009BB4460A9374A8259DE7BD05724467198E0A90|ydzS/2]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|D169C58739F17EE0D341D015592FF07CBBE1B6E1|AseR]: repression, [Pubmed|15948947], in [regulon|D169C58739F17EE0D341D015592FF07CBBE1B6E1|AseR regulon]

    • regulation

  • induced by As(III) ([protein|D169C58739F17EE0D341D015592FF07CBBE1B6E1|AseR]) [Pubmed|15948947]
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    Biological materials

    Mutant

  • MGNA-C141 (ydfA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2139 NBRP B. subtilis, Japan]

    • References

  • 15948947