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sufU [2018-01-03 10:02:42]
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sufU [2018-01-03 10:02:42]

iron-sulfur cluster scaffold protein, receives iron from [protein|88ACE6B79534338F7C72F107B35A0B2384007088|SufS], synthesis of Fe-S clusters
locus
BSU32680
pI
4.71
mw
16.02 kDa
protein length
147 aa Sequence Blast
gene length
441 bp Sequence Blast
function
synthesis of iron-sulfur clusters
product
iron-sulfur cluster scaffold protein
essential
yes
ec
2.-.-.-
synonyms
yurV,iscU
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.3|Biosynthesis of iron-sulfur clusters]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    3,357,011 → 3,357,454

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Protein family

  • nifU family (according to Swiss-Prot)

    • [SW|Cofactors]

  • zinc [Pubmed|24321018]

    • Structure

  • [PDB|2AZH]
  • [PDB|5XT5] (the [protein|88ACE6B79534338F7C72F107B35A0B2384007088|SufS]2-[protein|C0C30D2A6D3DF7A66063010044D370BD36D27DBF|SufU]2 complex) [pubmed|29235855]

    • Expression and Regulation

    Operons

    genes
    [gene|E966F3808222820C0644DC98F95765B89E6A2551|sufC]-[gene|1A9DA839AB77AF53958CB8426607BEF14F62B85E|sufD]-[gene|88ACE6B79534338F7C72F107B35A0B2384007088|sufS]-[gene|C0C30D2A6D3DF7A66063010044D370BD36D27DBF|sufU]-[gene|5991F051C5BAD61A0860BBC64A37DB9D16130998|sufB]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|22383849], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
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    Biological materials

    Mutant

  • MGNA-B584 (yurV::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1583 NBRP B. subtilis, Japan]

    • References

    Reviews

  • 28882201

    • Original publications

  • 20087498,20097860,12682299,20233928,20822158,22383849,21236255,24321018,21744456,27382962,29235855